An optimal stratified Simon two‐stage design
نویسندگان
چکیده
منابع مشابه
An optimal stratified Simon two-stage design
In Phase II oncology trials, therapies are increasingly being evaluated for their effectiveness in specific populations of interest. Such targeted trials require designs that allow for stratification based on the participants' molecular characterisation. A targeted design proposed by Jones and Holmgren (JH) Jones CL, Holmgren E: 'An adaptive Simon two-stage design for phase 2 studies of targete...
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ژورنال
عنوان ژورنال: Pharmaceutical Statistics
سال: 2016
ISSN: 1539-1604,1539-1612
DOI: 10.1002/pst.1742